National Certified Addiction Counselor, Level I (NCAC I) Practice Exam 2026 – Comprehensive All-in-One Guide to Exam Success!

The statement that no dependence is noted outside of PCP is true regarding dependence on LSD. LSD (lysergic acid diethylamide) is classified as a hallucinogenic substance, and research indicates that it does not produce the same kind of physical dependence seen with substances such as alcohol or opioids. While users may develop a tolerance to the effects of LSD with repeated use, this does not equate to physical dependence characterized by withdrawal symptoms when not using the substance.

Hallucinogens like LSD primarily affect the serotonin receptors in the brain rather than leading to physical addiction. Although some individuals may experience psychological cravings or a desire to use LSD again after an experience, the lack of withdrawal symptoms distinguishes it from substances known for creating physical dependence.

In contrast, statements about LSD commonly leading to physical dependence or that dependence occurs only after long-term use are misleading. There is also no evidence to support the idea that all hallucinogens are equally addictive, as dependence on various substances can vary significantly based on their pharmacological profiles and effects on the brain.